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- 详细信息
- 文献和实验
- 技术资料
- 库存:
339
- 英文名:
EGF816
- CAS号:
1508250-71-2
- 保质期:
2年
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
-20℃
- 规格:
1mL(10mM)|2mg|5mg|10mg|50mg|100mg
特别提示:包括EGFR抑制剂(EGF816)在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:EGFR抑制剂(EGF816)
英文名称:EGF816
产品货号:M00419
产品规格:1mL(10mM)|2mg|5mg|10mg|50mg|100mg
EGF816是一种新颖的EGFR抑制剂,对EGFR(L858R/790M)突变体的Ki和Kinact值分别为31nM和0.222min−1。
注:本品仅可用于科研实验,严禁用于临床医疗及其他用途!
CAS号:1508250-71-2
别名:Nazartinib
纯度:99.85%
分子式:C₂₆H₃₁ClN₆O₂
分子量:495.02
结构式:
储存条件:-20℃,有效期2年,溶入溶剂后-20℃请尽量在一个月内使用。
我公司销售的EGFR抑制剂(EGF816),EGF816,Nazartinib质量上佳,价格普惠,欢迎广大新老客户踊跃订购。
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文献和实验Assays to Monitor Degradation of the EGF Receptor
to conduct receptor downregulation assays are described. Monitoring of ubiquitination and degradation of the EGFR subsequent to stimulation with the receptor ligand EGF is described. Finally, protocols to quantitatively measure degradation of the EGFR
Phosphotyrosine Kinase Assays as a Prescreen for Inhibitors of EGFr
The epidermal growth factor receptor (EGFr) is a 170-kDa glycosylated transmembrane protein found in a wide variety of tissues (1 ). It is the receptor for epidermal growth factor (EGF), transforming growth factor α (TGFα), and other related
A Historical Perspective of the EGF Receptor and Related Systems
and physiological role that EGF plays during development and in adult animals led to the identification of its receptor (EGFR) as well as the other members of the EGF family of growth factors and their receptors. In this chapter we provide a historical overview
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