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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海经科化学科技有限公司
- 抗体英文名:
RTB | Ricin toxic B chain
- 规格:
50ul
| Immunogen Ricin B chain isolated from Ricinus communis var. Impala |
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Host Rabbit
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Clonality Polyclonal
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Purity Serum
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Format Lyophilized
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Quantity 50 µl
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Reconstitution
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| For reconstitution add 50 µl of sterile water. |
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Storage
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| Lyophilized antibody can be stored at -20°C for up to 3 years. Re-constituted antibody can be stored at 4°C for several days to weeks. |
| Once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from lyophilized material adhering to the cap or sides of the tubes. |
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Tested applications ELISA (ELISA)
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Recommended dilution
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| 1: 10 000 (ELISA) |
名称:RTB | Ricin toxic B chain
货号:AS17 4144
品牌:Agrisera
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文献和实验Synthesis of Monensin Derivatives and Their Effect on the Activity of Ricin A-Chain Immunotoxins
and to help A-chain translocation to the cytosol (4 -5 ). Naturally occurring A-chain-like toxins (ribosome-inactivating proteins, or RIPs) have also been used as toxic components of cell-selective conjugates (6 -7 ). Unlike intact toxin conjugates, ricin
In Vitro Studies of Ricin A-Chain-Induced Vascular Leak Syndrome
The major dose-limiting toxicity associated with ricin-conjugated immunotoxins (ITs) is vascular leak syndrome (VLS). IT-induced VLS appears to be dose dependent, occurs 2–4 d posttreatment (1 –6 ), and is thought to be a result
蓖麻( Ricinus communis)种子含有的毒性外源凝集素。向小鼠腹腔内注入 LD50 100ng,无血球凝集作用。分子量为 65000的糖蛋白( pI7.1),有 A链〔分子量 32000, PI7.5,含糖量 2.4%(重量比)〕和 B链〔分子量 34000, PI4.8,含糖量 6.5%(重量比)〕并以 S-S链结合。蓖麻蛋白可使核糖体的 60S亚单位失活,这样 GTP. EF-1-氨酚 tRNA复合物就不能再与核糖体结合,以致抑制了蛋白质活体合成中多肽
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