- ￥6275
- Agrisera
- 瑞典
- AS13 2688
- 2025年07月28日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
上海经科化学科技有限公司
- 抗体英文名：
Saporin
- 规格：
100ul
| Immunogen |
| Saporin, whole molecule |
|
Host Rabbit
|
|
Clonality Polyclonal
|
|
Purity Serum
|
|
Format Lyophilized
|
|
Quantity 100 µl
|
|
Reconstitution For reconstitution add 100 µl of sterile water.
|
|
Storage For long term stability requires storage, preferably in small aliquots at -20ºC or lower.It is recommended that a thawed sample is stored at 4ºC for no longer than 2 weeks. Allocation of appropriate anti-bacterial agent can increase shelf life by several weeks. Diluted serum should be prepared as required. Glycerol (1:1) can be added to neat serum for additional stability if intended use does not prevent this.
|
|
Tested applications ELISA (ELISA), Immunihistochemistry (IHC), Immunofluorescence (IF), Western blot (WB)
|
|
Recommended dilution 1 : 200-1 : 2000 is recommended. Optimal dilutions/concentrations should be determined by the end user.
|
|
Expected | apparent MW
|
| 29.5 kDa |
名称：Saporin
货号：AS13 2688
品牌：Agrisera
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文献和实验New genes useful in suicide gene therapy are those encoding toxins such as plant ribosome-inactivating proteins (RIPs), which can irreversibly block protein synthesis, triggering apoptotic cell death. Plasmids expressing a cytosolic saporin
Comparison of Immunotoxins Bearing a Single Saporin Molecule with Multiple Toxin Conjugates
Immunotoxins (IT) constructed by conventional chemical means using heterobifunctional crosslinking reagents such as [N -succinimidyl 3-(2-pyridyldithio) propionate (SPDP) or 4-succinimidyloxycarbonyl-α methyl-α-(2-pyridyldithio) toluene (SMPT
a lectin B-chain for cell entry, and thus have a low toxicity for whole cells. Type I RIPs such as saporin can be easily purified (4 ) and have been successfully used to generate potent ITs, displaying antitumor activity both in vitro (5 ) and in vivo (6 ).
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