Anti-MCM10 Polyclonal Antibody

产品简介

单位	支
英文名称	Anti-MCM10 Polyclonal Antibody
别名	MCM10;CNA43;DNA43;PRO2249
中文名称	微小染色体维持蛋白10抗体
宿主	Rabbit
稀释比例	WB 1:500-2000. IHC 1:50-200. IF 1:50-100.
Gene ID	55388
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q7L590
蛋白分子量	98kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Nucleus
免疫原	Recombinant protein of human MCM10
亚型	IgG
纯化方法	Affinity purification
背景资料	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with MCM10 antibody diluted at 1:1000;Lane:MCF7