Anti-TRAF6 Polyclonal Antibody

Anti-TRAF6 Polyclonal Antibody

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  • ¥960 - 1600
  • Solarbio已认证
  • 北京
  • 2025年10月01日
  • Rabbit
  • Human Mouse Rat
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    • 详细信息
    • 技术资料
    • 免疫原

      Recombinant protein of human TRAF6

    • 亚型

      IgG

    • 形态

      液体

    • 保存条件

      Store at -20°C. Avoid freeze / thaw cycles.

    • 克隆性

      单克隆

    • 适应物种

      Human Mouse Rat

    • 目录编号

      K001779P

    • 库存

      999

    • 供应商

      北京索莱宝科技有限公司

    • 宿主

      Rabbit

    • 靶点

      TRAF6

    • 抗体英文名

      Anti-TRAF6 Polyclonal Antibody

    • 抗体名

      MGC:3310;RNF85

    • 规格

      50ul/100ul

    规格:50ul产品价格:¥960.0
    规格:100ul产品价格:¥1600.0
    产品简介
    单位
    英文名称 Anti-TRAF6 Polyclonal Antibody
    别名 MGC:3310;RNF85
    宿主 Rabbit
    稀释比例 IF 1:50-200.
    Gene ID 7189
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    Swiss Prot Q9Y4K3
    蛋白分子量 60kDa
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    亚细胞定位 Cytoplasm Nucleus
    免疫原 Recombinant protein of human TRAF6
    亚型 IgG
    性状 液体
    纯化方法 Affinity purification
    背景资料 The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.
    Public Immunogen Range Recombinant protein of human TRAF6
    克隆类型 Polyclonal Antibody
    交叉反应 Human
    应用 IF
    规格 50ul 100ul

    备注:
    以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
    These protocols are for reference only. Solarbio does not independently validate these methods.
    温馨提示:
    使用前请离心。如有问题请及时联系我们。
    Quick spin before use. If you have any questions, please contact us.
    实验图
    Anti-TRAF6 Polyclonal Antibody
    Western blot analysis with TRAF6 antibody diluted at 1:1000
    Anti-TRAF6 Polyclonal Antibody
    Immunohistochemistry of paraffin-embedded liver cancer(hu) using TRAF6 antibody at dilution of 1:100 (x100 lens��x200 lens).
    Anti-TRAF6 Polyclonal Antibody
    Immunofluorescence analysis of HeLa cell using TRAF6 antibody. Blue: DAPI for nuclear staining.
    Anti-TRAF6 Polyclonal Antibody
    宿主 Rabbit
    别名 MGC:3310;RNF85
    稀释比例 WB 1:500-2000. IHC 1:50-200. IF 1:50-200.
    蛋白分子量 60kDa
    Gene ID 7189
    保存 Store at -20°C. Avoid freeze / thaw cycles.
    储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
    纯化方法 Affinity purification
    亚型 IgG
    免疫原 Recombinant protein of human TRAF6
    性状 液体
    Public Immunogen Range Recombinant protein of human TRAF6
    Swiss Prot Q9Y4K3
    亚细胞定位 Cytoplasm Nucleus
    克隆类型 Polyclonal Antibody
    背景资料 The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain. Two alternatively spliced transcript variants, encoding an identical protein, have been reported.
    应用    WB IHC IF
    交叉反应    Human    Mouse    Rat
    规格    50ul    100ul

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