Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位
Cytoplasm Cytoskeleton Nucleus
免疫原
A synthetic peptide of human HSPA1A
亚型
IgG
性状
液体
纯化方法
Affinity purification
背景资料
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response.
Public Immunogen Range
145-195/641aa
克隆类型
Polyclonal Antibody
交叉反应
Human
应用
WB
规格
50ul 100ul
备注: 以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。 These protocols are for reference only. Solarbio does not independently validate these methods. 温馨提示: 使用前请离心。如有问题请及时联系我们。 Quick spin before use. If you have any questions, please contact us. 实验图 Western blot analysis with HS71A antibody at dilution at 1:1000