Anti-ANAPC5 Polyclonal Antibod

产品简介

单位	支
英文名称	Anti-ANAPC5 Polyclonal Antibody
别名	APC5
宿主	Rabbit
稀释比例	WB 1:500-2000.IHC 1:50-200.IP 1:50-100
Gene ID	51433
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	Q9UJX4
蛋白分子量	85kDa
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
亚细胞定位	Cytosol Nucleus
免疫原	Recombinant protein of human ANAPC5
亚型	IgG
性状	液体
纯化方法	Affinity purification
背景资料	This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
Public Immunogen Range	Recombinant protein of human ANAPC5
克隆类型	Polyclonal Antibody
交叉反应	Human Rat Mouse
应用	WB IP IHC
规格	50ul 100ul

备注：
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
温馨提示：
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
实验图

Western blot analysis with ANAPC5 antibody diluted at 1:1000

Immunohistochemistry of paraffin-embedded rat kidney using ANAPC5 antibody at dilution of 1:100 (x40 lens).