- ￥960 - 1600
- Solarbio
- 北京
- K000152M
- 2025年07月08日
- ICC ; IP ; IF ; WB
- Mouse
- Human Rat
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- 详细信息
- 技术资料
- 免疫原：
Purified recombinant human E2F-1 protein fragments expressed in E.coli.
- 亚型：
IgG2b
- 形态：
液体
- 保存条件：
Store at -20°C. Avoid freeze / thaw cycles.
- 克隆性：
单克隆
- 标记物：
详询
- 适应物种：
Human Rat
- 保质期：
详询
- 抗原来源：
详询
- 目录编号：
K000152M
- 级别：
详询
- 库存：
999
- 供应商：
北京索莱宝科技有限公司
- 宿主：
Mouse
- 应用范围：
ICC ; IP ; IF ; WB
- 浓度：
详询
- 靶点：
E2F-1
- 抗体英文名：
Anti-E2F-1 Monoclonal Antibody
- 抗体名：
E2F-1;RBAP1;RBBP3;RBP3
- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥960.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1600.0 |
产品简介
|
英文名称
|
Anti-E2F1 Monoclonal Antibody
|
|
靶标
|
E2F1
|
|
别名
|
E2F-1;RBAP1;RBBP3;RBP3
|
|
背景资料
|
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis.
|
|
Swiss Prot
|
Q01094
|
|
Gene ID
|
1869
|
|
亚细胞定位
|
Nucleus
|
|
宿主
|
Mouse
|
|
克隆类型
|
Monoclonal Antibody
|
|
亚型
|
IgG2b
|
|
克隆号
|
4G8-2C2-C12
|
|
交叉反应
|
Rat ; Mouse ; Human
|
|
蛋白分子量
|
47kDa
|
|
应用
|
ICC ; IP ; IF ; WB
|
|
稀释比例
|
WB 1:500-1000. IF 1:50-200. IP 1:20. ICC 1:50-200.
|
|
免疫原
|
Recombinant protein of human E2F1
|
|
纯化方法
|
Affinity purification
|
|
储存液
|
Buffer: PBS with 0.02% sodium azide, 0.5% BSA, 50% glycerol, pH7.3.
|
|
保存
|
Store at -20℃. Avoid freeze / thaw cycles.
|
|
规格
|
100ul ; 50ul
|
|
单位
|
支
|
以上数据均来自公开文献, Solarbio暂未进行独立验证, 仅供参考。
These protocols are for reference only. Solarbio does not independently validate these methods.
使用前请离心。如有问题请及时联系我们。
Quick spin before use. If you have any questions, please contact us.
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Anti-E2F-1 Monoclonal Antibody
￥960 - 1600
