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Recombinant HTLV-1 gp46

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  • ¥2700 - 21000
  • Prospecbio
  • 以色列
  • hiv-142
  • 2025年07月16日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      HTLV-1 gp46

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      100ug/0.5mg/1mg

    规格:100ug产品价格:¥2700.0
    规格:0.5mg产品价格:¥10500.0
    规格:1mg产品价格:¥21000.0

    产品细节图片1

    CATALOGUE NUMBER

    HIV-142

    INTRODUCTION

    Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).

    DESCRIPTION

    The E.Coli derived recombinant mosaic protein contains the gp46 immunodominant region, 21-313 amino acids; Mw on SDA-PAGE is 34.2kDa and fuse to 6 histidines at C-terminus.

    PURIFICATION METHOD

    HTLV-1 gp46 was purified by proprietary chromatographic technique.

    PURITY

    Protein is >90% pure as determined by SDS-PAGE.

    FORMULATION

    The protein solution contains 20mM Phosphate buffer pH 7.5.

    STABILITY

    HTLV-1 gp46 although stable at 4°C for 1 week, should be stored below -18°C. 
    Please prevent freeze thaw cycles.

    AMINO ACID SEQUENCE

    PSCCTLTVGV SSYHSKPCNP AQPVCSWTLD LLALSADRAL QPPCPNLVSY SSYHATYSLY LFPHWIKKPN RNGGGYYSAS YSDPCSLKCP YLGCQSWTCP YTGAVSSPYW KFQQDVNFTQ EVSHLNINLH FSKCGFPFSL LVDAPGYDPI WFLNTEPSQL PPTAPPLLSH SNLDHILEPS IPWKSKLLTL VQLTLQSTNY TCIVCIDRAS LSTWHVLYSP NVSVPSPSST PLLYPSLALP APHLTLPFNW THCFDPQIQA IVSSPCHNSL ILPPFSLSPV PTLGSRSRRA.

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    The E.Coli derived recombinant mosaic protein contains the gp46 immunodominant region, 21-313 amino acids; Mw on SDA-PAGE is 34.2kDa and fuse to 6 histidines at C-terminus.

    相关实验
    • Isolation and Confirmation of Human T-Cell Leukemia Virus Type 2 From Peripheral Blood Mononuclear Cells

      with recombinant and synthetic peptides are used as a primary screen for the infection. Antigen-capture systems have increased the sensitivity and accuracy in verification of HTLV-2 culture systems. The verification of HTLV-2 infection and detection of new strains

    • 【申请上传】Current Protocols in Immunology

      and Clones Unit 7.19 Generation and Maintenance of Cloned Human T Cell Lines Unit 7.20 Generation of HTLV-I-Transformed T Cell Lines Unit 7.21 Generation of T Cell Hybridomas Unit 7.22 Generation of Epstein-Barr Virus (EBV—Immortalized B Cell Lines

    • 分子肿瘤学一--分子肿瘤学名词选编

      方法。 Adult T cell leukemia(ATL) 成人T细胞白血病,一种在成年期发生的具有T细胞特征的白血病,由人类T细胞白血病病毒1(HTLV-1)XH 引起。 AIDS(Acuirde Immuno-Deficiency Syndrome) 艾滋病(获处性免疫缺陷综合征),在感染人类免疫缺陷病毒(HIV)过程中细胞免疫进性怀损伤引起的天严重免疫失调和最终衰竭。 Allele loss 等位基丧失。也称杂合性丧失(loss

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    文献支持
    Recombinant HTLV-1 gp46
    ¥2700 - 21000