Recombinant Human Phospholipid Scramblase 3产品图
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Recombinant Human Phospholipid

Scramblase 3
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  • ¥1080 - 45885
  • Prospecbio
  • 以色列
  • pro-1733
  • 2026年01月21日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件:

      for future use below -18°C

    • 保质期:

      See instructions

    • 英文名:

      PLSCR3

    • 库存:

      常规产品有备货

    • 供应商:

      上海经科化学科技有限公司

    • CAS号:

      无

    • 规格:

      5ug/25ug/1mg

    规格:5ug产品价格:¥1080.0
    规格:25ug产品价格:¥2415.0
    规格:1mg产品价格:¥45885.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-1733

    SYNONYMS

    Phospholipid scramblase 3, PL scramblase 3, Ca(2+)-dependent phospholipid scramblase 3.

    INTRODUCTION

    Phospholipid Scramblase 3, (PLSCR3) may mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions which results in a loss of phospholipid asymmetry in the plasma membrane. PLSCR3 may play a key role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. In addition, PLSCR3 seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. Among the diseases associated with PLSCR3 are brain ischemia, and ischemia.

    DESCRIPTION

    PLSCR3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 288 amino acids (1-265 a.a) and having a molecular mass of 30.9kDa.
    PLSCR3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered clear solution.

    FORMULATION

    PLSCR3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 10% glycerol and 0.4M urea.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please avoid freeze thaw cycles.

    PURITY

    Greater than 90% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    MG.S.SHHHHHH SSGLVPRGSH MGSMAGYLPP KGYAPSPPPP YPVTPGYPEP ALHPGPGQAP VPAQVPAPAP GFALFPSPGP VALGSAAPFL PLPGVPSGLE FLVQIDQILI HQKAERVETF LGWETCNRYE LRSGAGQPLG QAAEESNCCA RLCCGARRPL RVRLADPGDR EVLRLLRPLH CGCSCCPCGL QEMEVQAPPG TTIGHVLQTW HPFLPKFSIQ DADRQTVLRV VGPCWTCGCG TDTNFEVKTR DESRSVGRIS KQWGGLVREA LTDADDFGLQ FPLDLDVR

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
     

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    图标文献和实验
    该产品被引用文献
    PLSCR3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 288 amino acids (1-265 a.a) and having a molecular mass of 30.9kDa.
    PLSCR3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
    相关实验
    • Introduction of human 14-3-3 proteins

      of tyrosine and tryptophan hydroxylases and for inhibition of Ca2+/phospholipid-dependent protein kinase C.Northern blot analysis demonstrated widespread expression of the 14-3-3 protein eta chain in cultured cell lines derived from various human tumors

    • 【分享】Human press METHODS IN MOLECULAR BIOLOGY

      9. Protocols in Human Molecular Genetics. Edited by G. Methaw, 1991 10. Immunochemical Protocols. Edited by Manson, Margaret M., 1992 11. Practical Protein Chromatography Edited by Kenney, Andrew, 1992 12. Pulsed-Field Gel Electrophoresis Protocols

    • 【第92期】前沿靶点速递:每周医学研究精选

      L通过调节糖鞘脂等脂筏关键组分维持脂筏结构完整性,保障EGFR在膜脂筏中的定位与活化;CLPTM1L缺失导致EGFR被转运至溶酶体降解,下游mTOR、ERK信号通路被抑制。GBM原位移植模型证实靶向CLPTM1L可显著抑制肿瘤生长并延长生存期,为肿瘤代谢干预提供了潜在新靶点。 推荐产品 靶点 重组蛋白 货号 CLPTM1L Recombinant Human Lipid scramblase CLPTM1L (CLPTM1L), partial CSB-MP

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    文献支持
    Recombinant Human Phospholipid Scramblase 3
    ¥1080 - 45885