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Recombinant Human Fibronectin

Type III Domain Containing 5, Yeast
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  • ￥1080 - 87906
  • Prospecbio
  • 以色列
  • pro-1663
  • 2026年01月16日
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    上海经科化学科技有限公司
    16 年钻石会员

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    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      FNDC5 Yeast

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      2ug/10ug/1mg

    规格：2ug产品价格：￥1080.0
    规格：10ug产品价格：￥2415.0
    规格：1mg产品价格：￥87906.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-1663

    SYNONYMS

    Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Irisin, FRCP2, FNDC5.

    INTRODUCTION

    Fibronectin Type III Domain Containing 5 (Irisin) is a newly discovered hormone, secreted into circulation by muscle, which acts on white adipocytes and promotes WAT “browning”. r-Irisin can reduce body weight and cause induction of brown adipocyte in vivo, including a capacity for thermogenic energy expenditure mediated by uncoupling protein 1 (UCP-1). Irisin mature protein is comprised of 110 amino acid residues and two potential glycosylation sites. High levels of Irisin can be found in the heart whereas Very low expression is found in the colon, pancreas and spleen, if any.

    DESCRIPTION

    Fibronectin Type III Domain Containing 5 Human Recombinant produced in yeast is a glycosylated, polypeptide chain containing 110 amino acids and having a molecular mass of 20-25 kDa.
    FNDC5 is purified by proprietary chromatographic techniques.

    SOURCE

     Yeast.

    PHYSICAL APPEARANCE

    Sterile Filtered White lyophilized (freeze-dried) powder.

    FORMULATION

    The FNDC5 was lyophilized from 0.45 µm filtered solution in PBS.

    SOLUBILITY

    It is recommended to reconstitute the lyophilized Fibronectin Type III Domain Containing 5 in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    STABILITY

    Lyophilized Fibronectin Type III Domain Containing 5 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FNDC5 should be stored at 4°C between 2-7 days and for future use below -18°C.
    Please prevent freeze-thaw cycles.

    PURITY

    Greater than 98.0% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    S_P__S__A__P__V__N__V__T__V__R__H__L__K__A__N__S__A__V__V__S_

    W__D__V__L__E__D__E__V__V__I__G__F__A__I__S__Q__Q__K__K__D _V__R__M__L__R__F__I__Q__E__V__N__T__T__T__R__S__C__A__L__W_

    _ D__L__E__E__D__T__E__Y__I__V__H__V__Q__A__I__S__I__Q__G__Q_

    S__P__A__S__E__P__V__L__F__K__T__P__R__E__A__E__K__M__A__S_ K

    __N__K__D__E__V__T__M__K__E.

    BIOLOGICAL ACTIVITY

    The biological activity of recombinant human irisin was measured by the ability to induce UCP-1 expression of adipocytes. The specific activity is 10ng/ml.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    Fibronectin Type III Domain Containing 5 Human Recombinant produced in yeast is a glycosylated, polypeptide chain containing 110 amino acids and having a molecular mass of 20-25 kDa.
    FNDC5 is purified by proprietary chromatographic techniques.

    相关实验

    • Recombinant Collagen Trimers from Insect Cells and Yeast

      have been unsuccessful, but active recombinant human prolyl 4-hydroxylase has been produced in insect cells and yeast by coexpression of its α- and β-subunits (7 ,7 ). We have recently shown that recombinant human type III collagen with a stable triple helix

    • Introduction of human 14-3-3 proteins

      terminus of GPIb-alpha,as indicated by antibody inhibition and direct binding of 14-3-3zeta to synthetic GPIb-alpha cytoplasmic domain peptides.The 14-3-3zeta binds to recombinant wild type GPIb-IX but not to the GPIb-alpha mutants lacking C-terminal

    • GPI蛋白

      domain 428 490 ig-like c2-type domain. domain 518 589 ig-like c2-type domain. domain 599 608 hinge (potential). domain 601 607 gly/pro-rich. domain 608 709 fibronectin type-iii. domain 710 811 fibronectin type-iii. domain 812 912 fibronectin

    查看更多相关实验 >

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    文献支持
    Recombinant Human Fibronectin Type III Domain Containing 5, Yeast
    ￥1080 - 87906