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Recombinant Human Bartter Synd

rome Infantile with Sensorineural Deafness
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  • ¥1080 - 20286
  • Prospecbio
  • 以色列
  • pro-1551
  • 2026年01月11日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      BSND

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      2ug/10ug/100ug

    规格:2ug产品价格:¥1080.0
    规格:10ug产品价格:¥2415.0
    规格:100ug产品价格:¥20286.0

    产品细节图片1

    CATALOGUE NUMBER

    PRO-1551

    SYNONYMS

    Bartter Syndrome Infantile With Sensorineural Deafness (Barttin) , Deafness Autosomal Recessive 73, DFNB73, BART, barttin.

    INTRODUCTION

    BSND is a vital beta subunit for CLC chloride channels. These heteromeric channels are restricted to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. BSND gene mutations are linked with Bartter syndrome with sensorineural deafness.

    DESCRIPTION

    BSND Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 290 amino acids (54-320) and having a molecular mass of 31.7kDa.
    BSND is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered clear solution.

    FORMULATION

    The BSND solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 10% glycerol.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 90% as determined by SDS-PAGE.

    AMINO ACID SEQUENCE

    MG.S/SHHHHHH SSGLVPRGSH MGSCQCYPKI TFVPADSDFQ GILSPKAMGL LENGLAAEMK SPSPQPPYVR LWEEAAYDQS LPDFSHIQMK VMSYSEDHRS LLAPEMGQPK LGTSDGGEGG PGDVQAWMEA AVVIHKGSDE SEGERRLTQS WPGPLACPQG PAPLASFQDD LDMDSSEG.S/S PNASPHDREE ACSPQQEPQG CRCPLDRFQD FALIDAPTLE DEPQEGQQWE IALPNNWQRY PRTKVEEKEA SDTGGEEPEK EEEDLYYGLP DGAGDLLPDK ELGFEPDTQG

    SAFETY DATA SHEET

    SDS

    USAGE

    ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    BSND is a vital beta subunit for CLC chloride channels. These heteromeric channels are restricted to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. BSND gene mutations are linked with Bartter syndrome with sensorineural deafness.

    相关实验
    • Discovery Genetics: The History and Future of Spontaneous Mutation Research

      .J., Washburn, L.L., Smith, R.S., Andersen, S.G., Swank, R.T., Dell'Angelica, E.C., Bonifacino, J.S., Eicher, E.M., and Peters, L.L. 2000. Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky‐Pudlak syndrome by an AP

    • Real‐Time Quantitative PCR Analysis of Mitochondrial DNA Content

      ., Santorelli, F.M., van Rooij, A., Vermunt‐de Koning, D., Morava, E., and Wevers, R.A. 2007. SUCLA2 mutations are associated with mild methylmalonic aciduria, Leigh‐like encephalomyopathy, dystonia and deafness. Brain 130:862‐874

    • Musculoskeletal System

      . BONES The human skeleton contains 206 bones, which are composed of inorganic salts (primarily calcium and phosphate), embedded in a framework of collagen fibers. Bone shape and structure Bones are classified

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    文献支持
    Recombinant Human Bartter Syndrome Infantile with Sensorineural Deafness
    ¥1080 - 20286