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Recombinant Human Protein kina

se Casein Kinase 2 alpha 1, His Tag
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  • ¥1080 - 87906
  • Prospecbio
  • 以色列
  • pka-225
  • 2026年01月09日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      CSNK2A1 His

    • 库存

      常规产品有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      2ug/10ug/1mg

    规格:2ug产品价格:¥1080.0
    规格:10ug产品价格:¥2415.0
    规格:1mg产品价格:¥87906.0

    产品细节图片1

    CATALOGUE NUMBER

    PKA-225

    SYNONYMS

    Casein kinase II subunit alpha, EC 2.7.11.1, CK II, CK2A1, CKII alpha, CSNK2A1, PKCK2, CSK21.

    INTRODUCTION

    The Casein kinase 2 (EC2.7.11.1) is a serine/threonine-selective protein kinasethat is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cyclecontrol, DNA repair, regulation of the circadian rhythmand other cellular processes.
    Casein kinase 2 activity has been reported to be activated following Wnt signaling pathwayactivation. A Pertussis toxin-sensitive G proteinand Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2.
    Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm.

    DESCRIPTION

    CK2A Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain encoding the sequence of 411 amino acids and having a molecular mass of 47.3 kDa.
    Casein Kinase 2 alpha subunit is purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered clear solution.

    FORMULATION

    CSNK2A1 is supplied in 20mM Tris pH-8.0 , 500mM NaCl, 1mM DTT and 50% glycerol.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks. 
    Store, frozen at -20°C for longer periods of time. 
    Avoid multiple freeze-thaw cycles.

    AMINO ACID SEQUENCE

    MG./S-SHHHHHH SSGLVPRGSH MSGPVPSRAR VYTDVNTHRP REYWDYESHV VEWGNQDDYQLVRKLGRGKY SEVFEAINIT NNEKVVVKIL KPVKKKKIKR EIKILENLRG GPNIITLADI VKDPVSRTPA LVFEHVNNTD FKQLYQTLTD YDIRFYMYEI LKALDYCHSM GIMHRDVKPH NVMIDHEHRK LRLIDWGLAE FYHPGQEYNV RVASRYFKGP ELLVDYQMYD YSLDMWSLGC MLASMIFRKE PFFHGHDNYD QLVRIAKVLG TEDLYDYIDK YNIELDPRFN DILGRHSRKRWERFVHSENQ HLVSPEALDF LDKLLRYDHQ SRLTAREAME HPYFYTVVKD QARMG./S-SSMP GGSTPVSSAN MMSGISSVPT PSPLGPLAGS PVIAAANPLG MPVPAAAGAQ Q.

    PURITY

    Greater than 90% as determined by SDS-PAGE.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    CK2A Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain encoding the sequence of 411 amino acids and having a molecular mass of 47.3 kDa.
    Casein Kinase 2 alpha subunit is purified by proprietary chromatographic techniques.

    相关实验
    • Introduction of human 14-3-3 proteins

      whose members have been shown to activate tyrosine and tryptophan hydroxylases,inhibit protein kinase C and possess phospholipase A2 activity in vitro.We have isolated and analyzed a 14-3-3 protein cDNA clone (H14-3-3)from a human fetal brain cDNA library

    • 蛋白激酶家族:药物研发的关键靶点

      .medchemexpress.cn/recombinant-proteins/egfr-protein-human-c797s-t790m-l858r-sf9-gst.html)、预复合物形式如 CDK4-CCND1 (www.medchemexpress.cn/recombinant-proteins/cdk4-ccnd1-protein-human-sf9-gst-flag-his.html)等。 二、激酶系列化合物库及激酶谱筛选服务(www.medchemexpress.cn/kinase-screening

    • Identifying Protein Interactions by Hydroxyl‐Radical Protein Footprinting

      containing a protein kinase recognition motif, His6‐tag and hemagglutinin epitope. Gene 166:177‐178.    Kim, K., Rhee, S.G., and Stadtman, E.R. 1985. Nonenzymatic cleavage of proteins

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    文献支持
    Recombinant Human Protein kinase Casein Kinase 2 alpha 1, His Tag
    ¥1080 - 87906