产品封面图
文献支持

Recombinant Human Macrophage I

nflammatory protein-1 alpha (CCL3)
收藏
  • ￥1080 - 45885
  • Prospecbio
  • 以色列
  • chm-233
  • 2025年12月29日
    avatar
    上海经科化学科技有限公司
    16 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      MIP 1a

    • 库存：

      常规产品有备货

    • 供应商：

      上海经科化学科技有限公司

    • CAS号：

      无

    • 规格：

      5ug/20ug/1mg

    规格：5ug产品价格：￥1080.0
    规格：20ug产品价格：￥2415.0
    规格：1mg产品价格：￥45885.0

     

    CATALOGUE NUMBER

    CHM-233

    SYNONYMS

    Small inducible cytokine A3, CCL3, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, Tonsillar lymphocyte LD78 alpha protein, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, SIS-beta, PAT 464.1, chemokine (C-C motif) ligand 3, MIP1A, SCYA3, G0S19-1, LD78ALPHA.

    INTRODUCTION

    Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP-1a and MIP-1b that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes (neutrophils, eosinophilsand basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1 (IL-1), IL-6 and TNF-a from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17.

    DESCRIPTION

    Macrophage Inflammatory Protein-1 alpha Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7820 Dalton.
    The MIP-1a is purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered White lyophilized (freeze-dried) powder.

    FORMULATION

    The protein was lyophilized from 0.55 mg/ml solution containing no additives.

    SOLUBILITY

    It is recommended to reconstitute the lyophilized Macrophage Inflammatory Protein-1a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    STABILITY

    Lyophilized MIP-1a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL3 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please prevent freeze-thaw cycles.

    PURITY

    Greater than 98.0% as determined by:
    (a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.

    AMINO ACID SEQUENCE

    The sequence of the first five N-terminal amino acids was determined and was found to be, Ala-Ser-Leu-Ala-Ala.

    BIOLOGICAL ACTIVITY

    The Activity is calculated by the ability of chemo-attraction of Human monocytes using 1-10ng/ml corresponding to a Specific Activity of 100,000-1,000,000IU/mg.

    SAFETY DATA SHEET

    SDS

    USAGE

    Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    Macrophage Inflammatory Protein-1 alpha Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7820 Dalton.
    The MIP-1a is purified by proprietary chromatographic techniques.

    相关实验

    • Introduction of human 14-3-3 proteins

      The human and bovine 14-3-3 eta protein mRNAs are highly conservedEvolutionary conservation of the 14-3-3 proteinExpression and structural analysis of 14-3-3 proteinsCrystal structure of the zeta isoform of the 14-3-3 proteinStructure of a 14

    • MAPK signaling pathway - Homo sapiens (human)

      相关专题 MAPK信号通路专题 MAPK signaling pathway - Homo sapiens (human)：The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various Cell ular functions, including cell

    • Identifying Protein Interactions by Hydroxyl‐Radical Protein Footprinting

      of phosphorylation sites in proteins: Construction of a phosphorylatable human interferon alpha. Proc. Natl. Acad. Sci. U.S.A. 86:558‐562.    Loizos, N. and Darst, S.A. 1998. Mapping protein

    查看更多相关实验 >

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    Recombinant Human Macrophage Inflammatory protein-1 alpha (CCL3), His Tag
    ￥1080
    上海经科化学科技有限公司
    2025年12月29日询价
    Recombinant Human Macrophage Inflammatory Protein 4 Alpha (MIP4a)
    询价
    默瑞（上海）生物科技有限公司
    2025年07月16日询价
    Macrophage Inflammatory Protein-1 alpha (Human, rDNA derived)
    ￥650
    南京北鱼生物科技有限公司
    2025年06月10日询价
    Immunotag™ Rat MIP-1α/CCL3 (Macrophage Inflammatory Protein 1 Alpha) ELISA
    ￥12568.50
    北京孚博生物科技有限公司
    2025年07月12日询价
    Macrophage Inflammatory Protein-5 (human)
    ￥5689
    爱必信(上海)生物科技有限公司
    2025年06月28日询价
    文献支持
    Recombinant Human Macrophage Inflammatory protein-1 alpha (CCL3)
    ￥1080 - 45885