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Recombinant Human Growth Hormo

ne Binding Protein, His Tag
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  • ¥1080 - 87906
  • Prospecbio
  • 以色列
  • cyt-921
  • 2025年07月19日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      for future use below -18°C

    • 保质期

      See instructions

    • 英文名

      G/.H-BP, His

    • 库存

      部分小规格有备货

    • 供应商

      上海经科化学科技有限公司

    • CAS号

    • 规格

      2ug/10ug/1mg

    规格:2ug产品价格:¥1080.0
    规格:10ug产品价格:¥2415.0
    规格:1mg产品价格:¥87906.0

    产品细节图片1

    CATALOGUE NUMBER

    CYT-921

    SYNONYMS

    Growth Hormone Receptor, Growth Hormone Binding Protein, Somatotropin Receptor GH Receptor, Serum Binding Protein, G/.H-BP, GHIP.

    INTRODUCTION

    Growth hormone receptor, also known as GHR is part of the cytokine receptor family.  GHR binds 2 receptor molecules and in this manner induces signal transduction through receptor dimerization. Furthermore, at high concentrations, growth hormone performs as an antagonist since there is a large difference in affinities at the respective binding sites. The antagonist action can be enhanced further by reducing binding in the low affinity binding site.

    DESCRIPTION

    G/.H-BP produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 254 amino acids (19-264a.a.) and having a molecular mass of 29.4kDa.
    G/.H-BP is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

    SOURCE

    Sf9, Insect cells.

    PHYSICAL APPEARANCE

    Sterile filtered colorless solution.

    FORMULATION

    G/.H-BP protein solution (1mg/ml) contains phosphate buffered saline (pH7.4) and 10% glycerol.

    STABILITY

    Store at 4°C if entire vial will be used within 2-4 weeks.
    Store, frozen at -20°C for longer periods of time.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Avoid multiple freeze-thaw cycles.

    PURITY

    Greater than 95.0% as determined by SDS-PAGE.

    SAFETY DATA SHEET

    SDS

    BIOLOGICAL ACTIVITY

    The ED50 range ≤ 10ng/ml and is measured by ability to inhibit GH-induced proliferation assay using Nb2-11 Rat lymphoma cells in the presence of 1.25ng/ml of human growth hormone.

    AMINO ACID SEQUENCE

    FSGSEATAAI LSRAPWSLQS VNPGLKTNSS KEPKFTKCRS PERETFSCHW TDEVHHGTKN LGPIQLFYTR RNTQEWTQEW KECPDYVSAG ENSCYFNSSF TSIWIPYCIK LTSNGGTVDE KCFSVDEIVQ PDPPIALNWT LLNVSLTGIH ADIQVRWEAP RNADIQKGWM VLEYELQYKE
    VNETKWKMMD PILTTSVPVY SLKVDKEYEV RVRSKQRNSG NYGEFSEVLY VTLPQMSQFT CEEDFYLEHH HHHH.

    USAGE

    ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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    图标文献和实验
    该产品被引用文献

    G/.H-BP produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 254 amino acids (19-264a.a.) and having a molecular mass of 29.4kDa.
    G/.H-BP is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

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    文献支持
    Recombinant Human Growth Hormone Binding Protein, His Tag
    ¥1080 - 87906