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- 湖北武汉
- E-AB-F1012I
- 2025年07月10日
- FCM
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 亚型：
Mouse IgG1, κ
- 形态：
液体
- 保存条件：
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
- 克隆性：
Monoclonal
- 标记物：
PE/Cyanine5.5
- 适应物种：
Human
- 保质期：
12个月
- 目录编号：
E-AB-F1012I
- 级别：
科研
- 库存：
999
- 供应商：
武汉伊莱瑞特生物科技股份有限公司
- 宿主：
Mouse
- 应用范围：
FCM
- 抗体英文名：
PE/Cyanine5.5 Anti-Human CD86 Antibody[BU63]_货号:E-AB-F1012I
- 抗体名：
PE/Cyanine5.5 Anti-Human CD86 Antibody流式抗体[BU63]_货号:E-AB-F1012I
- 规格：
100Tests/20Tests/100Tests×2
| 规格： | 100Tests | 产品价格： | ￥3120.0 |
|---|---|---|---|
| 规格： | 20Tests | 产品价格： | ￥1200.0 |
| 规格： | 100Tests×2 | 产品价格： | ￥4680.0 |
货号：E-AB-F1012I
| Background |
CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, monocytes/macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is the ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce costimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can bind to CD152 as well, also known as CTLA-4, to deliver an inhibitory signal to T cells.
|
| Alternate Names |
T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
|
| Swissprot |
P42081
|
| Gene ID |
942
|
| Clone No |
BU63
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Application |
FCM
|
| Isotype |
Mouse IgG1, κ
|
| Isotype Control |
PE/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
|
| Conjugation |
PE/Cyanine5.5
|
| Conjugation Information |
PE/Cyanine5.5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 690 nm (e.g., a 690/50 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration date |
12个月
|
| Shipping |
冰袋
|
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文献详情查看>>>>
Stimulation of Anti-HIV-1 Cytotoxic T Lymphocytes by Dendritic Cells
molecules CD40, CD80, and CD86 (5 ,6 ), and production of cytokines such as interleukin-12 (IL-12) (7 -9 ), IL-6 (10 ), and interferon α (IFN-α) (10 ,11 ). Moreover, DC can process antigens in various forms by different pathways and induce high levels
Collection, Separation, and Activation of Human T Lymphocytes
and is constitutively expressed on the surface of both CD4+ and CD8+ T lymphocytes (5 ,6 ). CD28 and its homolog CTLA-4 bind the natural ligands B7.1 and B7.2 (also known as CD80 and CD86, respectively), which are present on antigen presenting cells (APCs
Phycoerythrin conjugation protocol
and Centricon concentrators. Add 0.5% sodium azide. Store at 4 °C protected from light. Do not freeze. Figure 1. Analysis of column eluate fractions from PE conjugation of monoclonal antibody IB4 (murine IgG2a, anti-human CD
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