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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Synthetic peptide common to most PDE4 subtypes: PDE4A, PDE4D, PDE4B
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Polyclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Mouse, Rat, Chicken, Monkey
- 保质期:
12 months from the shipping date of the product.
- 目录编号:
GTX14628
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
WB, ICC/IF, IP, ELISA, IHC
- 浓度:
0.62 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
This antibody detects all known PDE4 A and D variants including PDE4A1, A5, Ax, A8 and PDE4D1-D5. It has low affinity for PDE4B variants.
- 抗体英文名:
PDE4 antibody
- 抗体名:
PDE4 抗体
- 规格:
100 μg
WB analysis of rat cortical membrane lysate using GTX14628 PDE4 antibody.
Dilution : 1:500
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文献和实验Generation of PDE4 Knockout Mice by Gene Targeting
by homologous recombination in mouse ES cells in vitro has been established as a powerful means of altering specific loci in the mouse genome. As a result, gene function can be studied in vivo. By applying this technology, targeted disruption of PDE4 alleles
Renaturation of the Catalytic Domain of PDE4A Expressed in Escherichia coli as Inclusion Bodies
bodies and optimal conditions have to be determined empirically for any given protein. Here, we describe a simple and efficient refolding protocol for the catalytic domain of type 4 cyclic nucleotide phosphodiesterases (PDE4s). This method
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
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