Amyloid beta (1-42 specific) m

gene_symbol：null
predicted_size：null
Uniprot ID
description：Amyloid beta (1-42 specific) mouse monoclonal antibody, clone CA9 10C11, Aff - Purified
clonality：Monoclonal
product_type(primary antibody, secondy antibody ,tag antibody,Loding Control...)：Primary Antibodies
background：Amyloid beta peptide 42 (Aβ42) is best known for its role in the formation of senile plaques in the brain of patients with Alzheimer’s disease. Aβ42 and Aβ40 are the two major amyloid peptides that are produced after cleavage of amyloid precursor protein by secretases. Aβ42 (42 amino acids) is very fibrillogenic. The beta pleated structure of Aβ42 constituents the initial and key component of the insoluble amyloid fibril in senile plaque. It is widely accepted that Aβ42 contributes to the pathogenesis of Alzheimer’s disease. One proposition is that the deposition of amyloid fibril onto the brain tissue results in Alzheimer’s disease. Another is that the neurotoxicity of Aβ42 oligomer is the cause of the disease.
immunogen：KLH conjugated to a short peptide corresponding to the C-terminal sequence of beta amyloid peptide 42
recommended_dilution：ELISA: For sandwich ELISA use clone NT 4A2, Cat.-No AM26042PU-N as cupture antibody. The antibody can detect Aβ42 in Sandwich ELISA assay. Western blot Dot blot
predicted_size：null
buffer：0.01M PBS pH7.2; State: Aff - Purified; State: Lyophilized purified IgG fraction
host_species：Mouse
applications：ELISA, WB
reactivities：Human, Mouse, Primate, Rat