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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG
- 保存条件:
Store at -20 °C
- 库存:
20-60
- 供应商:
上海邦景
- 浓度:
1mg/ml
- 抗体英文名:
p19ARF
- 规格:
0.1ml
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文献和实验Evaluation of Alterations in the Tumor Suppressor Genes INK4A and INK4B in Human Bladder Tumors
from the presence of a second INK4A product, termed p19 ARF or p14 ARF in humans (ARF is the acronym for alternative reading frame) (17 –20 ) (Fig. 1 ). The p19 ARF blocks the mdm2 -induced p53 degradation and transactivational silencing (21 ,22 ). The INK
The Regulation of Tumor Suppressor Genes by Oncogenes
-1/WAF1/mda6 (p21), p27 Kip-1 (p27), p16 INK4a (p16), and p19 ARF (p19), play the role of negative regulators of the cell cycle (1 –5 ). In contrast, mutation of protooncogenes such as the epidermal growth factor receptor (EGFR) (6 ), ErbB2 (Neu
Mechanism and Method for Generating Tumor-Free iPS Cells Using Intronic MicroRNA miR-302 Induction
during G1–S phase transition. Additionally, miR-302 also silenced BMI-1, a cancer stem cell marker gene, to promote the expression of two senescence-associated tumor suppressor genes, p16Ink4a and p14/p19Arf. Together, the combinatory effect of reducing G1–S
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