产品英文名称: Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide A
英文简称: SNRPA
中文名称: 重组人U1小核核糖核蛋白肽A(SNRPA)
背景资料: SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5’ splice site of precursor mRNAs and is essential for splicing. The SNRPA protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and is involved in the coupling of splicing and polyadenylation. SNRPA binds stem loop II of U1 snRNA. SNRPA is the first snRNP to interact with pre-mRNA. This interaction is vital for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP.
产品描述: SNRPA Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 32,102 Dalton. SNRPA is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
来源宿主: Sf9 昆虫细胞重组表达