重组小鼠α-synuclein蛋白

产品英文名称：
Recombinant Mouse Alpha-Synuclein

英文简称:
mSNCA

中文名称:
重组小鼠α-synuclein蛋白

背景资料:
a-Synuclein （amino acids 1-140）， an acidic neuronal protein of 140 amino acids， is extremely heat-resistant and is natively unfolded with an extended structure primarily composed of random coils. a-synuclein has bSNCA Recombinant Mouse produced in E.Coli is a single， non-glycosylated polypeptide chain containing 140 amino acids （1-140 a.a.） and having a molecular mass of 14.4 kDa. The SNCA is purified by proprietary chromatographic techniques.n suMDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA.ested to be implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders， and more recently， to be an important regulatory component of vesicular transport in neuronal cells. Moreover， recent studies have shown that a-synuclein has chaperone activity and that this activity is lost upon removing its C-terminal acidic tail （amino acids 96-140）.

产品描述:
SNCA Recombinant Mouse produced in E.Coli is a single， non-glycosylated polypeptide chain containing 140 amino acids （1-140 a.a.） and having a molecular mass of 14.4 kDa. The SNCA is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:
MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGNIAA ATGFVKKDQM GKGEEGYPQE GILEDMPVDP GSEAYEMPSE EGYQDYEPEA.

溶解建议:
Sterile filtered colorless solution. The SNCA protein contains 20mM Tris-HCl buffer （pH 7.5）， and 10% glycerol.

保存建议：
Store at 4℃ if entire vial will be used within 2-4 weeks. Store， frozen at -20℃ for longer periods of time. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Avoid multiple freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。
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