重组HIV-2 gp36 （390-702）

产品英文名称：
Recombinant HIV-2 gp36 （390-702）

英文简称:
HIV-2 gp36 （390-702）

中文名称:
重组HIV-2 gp36 （390-702）

背景资料:
HIV-1 and HIV-2 appear to package their RNA di大肠杆菌中重组表达erently. HIV-1 binds to any appropriate RNA whereas HIV-2 preferentially binds to mRNA which creates the Gag protein itself. This means that HIV-1 is better able to mutate. HIV-2 is transmitted in the same ways as HIV-1: Through exposure to bodily fluids such as blood， semen， tears and vaginal fluids. Immunodeficiency develops more slowly with HIV-2. HIV-2 is less infectious in the early stages of the virus than with HIV-1. The infectiousness of HIV-2 increases as the virus progresses. Major di大肠杆菌中重组表达erences include reduced pathogenicity of HIV-2 relative to HIV-1， enhanced immune control of HIV-2 infection and often some degrHIV-2 gp36 34 kDa recombinant- contains the sequence of HIV-2 envelope immunodominant regions gp36， amino acids 390-702. The protein is fused to beta-galactosidase （114 kDa） at N-terminus. of CD4-independence. Despite considerable sequence and phenotypic di大肠杆菌中重组表达erences betwHIV-2 gp36 34 kDa recombinant- contains the sequence of HIV-2 envelope immunodominant regions gp36， amino acids 390-702. The protein is fused to beta-galactosidase （114 kDa） at N-terminus.n HIV-1 and 2 envelopes， structurally they are quite similar. Both membrane-anchored proteins eventually form the 6-helix bundles from the N-terminal and C-terminal regions of the ectodomain， which is common to many viral and cellular fusion proteins and which sHIV-2 gp36 34 kDa recombinant- contains the sequence of HIV-2 envelope immunodominant regions gp36， amino acids 390-702. The protein is fused to beta-galactosidase （114 kDa） at N-terminus.ms to drive fusion. HIV-1 gp41 helical regions can form more stable 6-helix bundles than HIV-2 gp41 helical regions however HIV-2 fusion occurs at a lower threshold temperature （25°C）， does not require Ca2+ in the medium， is insensitive to treatment of target cells with cytochalasin B， and is not a大肠杆菌中重组表达ected by target membrane glycosphingolipid composition.

产品描述:
HIV-2 gp36 34 kDa recombinant- contains the sequence of HIV-2 envelope immunodominant regions gp36， amino acids 390-702. The protein is fused to beta-galactosidase （114 kDa） at N-terminus.
来源宿主:
大肠杆菌中重组表达

序列:


溶解建议:
提供的重组HIV-2 gp36 （390-702）产品为无菌的无色透明溶液形式.该产品已溶解在含0.01M Na2CO3， 0.01M Na3EDTA， 0.014 甲基巯基乙醇， 0.02% 十二烷基肌氨酸钠溶液.

保存建议：
Protein should be stored at 4℃. Refrigerate Upon arrival. DO NOT FREEZE.
其他简介：

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