重组链霉亲和素（37-159氨基酸），HIS标签

产品英文名称：
Recombinant Rhesus Macaque S100 Calcium Binding Protein B

英文简称:
rmS100b

中文名称:
重组猕猴S100钙粘合蛋白B

背景资料:
S100b is a member of the S100 family of proteins which are a family of EF-hand calcium binding proteins that exist mostly as dimers of the 20 currently identified individual S100 monomers. The S100B homodimer is expressed in cells of the central nervous system， glial cells and in certain peripheral cells e.g. Schwann cells， melanocytes， adipocytes and chondrocytes. S100 proteins are localized either in the cytoplasm or the nucleus of a wide range of cells. S100 proteins are involved in the regulation of a number of cellular processes such as cell cycle progression and di大肠杆菌中重组表达erentiation. There are at least 13 members in the S100 gene family， which are located as a cluster on chromosome 1q21； however， S100b is located at 21q22.3. The determination of S100B in serum levels may be used to monitor the extent of brain injury and malignant melanoma. S100b proteins may have a role in Neurite extension， proliferation of melanoma cells， stimulation of Ca2+ fluxes， inhibition of PKC-mediated phosphorylation， astrocytosis and axonal proliferation， and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of the S100b gene are implicated in several neurological， neoplastic， and other types of diseases， including Alzheimer’s disease， Down’s syndrome， epilepsy， amyotrophic lateral sclerosis， melanoma， and type I diabetes.

产品描述:
S100B Rhesus Macaque Recombinant produced in E.Coli is a single， non-glycosylated， polypeptide chain containing 91 amino acids and having a molecular mass of 10.7kDa. The S100B Rhesus Macaque is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:
SELEKAMVAL IDVFHQYSGR EGDKHKLKKS ELKELINNEL SHFLEEIKEQ EVVDKVMETL DSDGDGECDF QEFMAFVAMV TTACHEFFEH E

溶解建议:
提供的重组猕猴S100钙粘合蛋白B产品形式为冻干粉末.建议用无菌处理的18M-cm水溶解重组猕猴S100钙粘合蛋白B，浓度不低于100ug/ml.后继实验过程中可根据实验要求进一步稀释.

保存建议：
重组猕猴S100钙粘合蛋白B产品在室温保存3周，于-18°C以下长期保存.一旦溶解，于4°C保存2-7天.避免反复冻融
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际一流的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。