重组人基质相互作用分子1

产品英文名称：
Recombinant Human Ferritin Heavy Chain

英文简称:
Ferritin Heavy

中文名称:
重组人肝铁蛋白重链

背景资料:
Ferritin is a fairly large， iron-storage heteropolymeric protein composed of 2 subunit types， light Ferritin & heavy Ferritin polypeptides， which is expressed in most kinds of cells and co-assemble in di大肠杆菌中重组表达erent proportion in a tissue-specific manner. Ferritin is composed of 24 self-assembled polypeptide subunits of the heavy and light ferritin chains and is characterized by the capacity to remove Fe （II） from solution in the presence of oxygen. Ferritin light polypeptide protein is the main intracellular iron storage protein in prokaryotes and eukaryotes. Variation in ferritin subunit composition influence the rates of iron uptake and release in various tissues. A key function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyper ferrit anemia-cataract syndrome. Ferritin stores iron in a soluble， nontoxic， readily accessible form. Ferritin is nFTH1 Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 183 amino acids and having a molecular mass of 21 kDa.ded for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after it has bFTH1 Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 183 amino acids and having a molecular mass of 21 kDa.n oxidized.

产品描述:
FTH1 Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 183 amino acids and having a molecular mass of 21 kDa.
来源宿主:
大肠杆菌中重组表达

序列:
MTTASTSQVR QNYHQDSEAA INRQINLELY ASYVYLSMSY YFDRDDVALK NFAKYFLHQS HEEREHAEKL MKLQNQRGGR IFLQDIKKPD CDDWESGLNA MECALHLEKN VNQSLLELHK LATDKNDPHL CDFIETHYLN EQVKAIKELG DHVTNLRKMG APESGLAEYL FDKHTLGDSD NES.

溶解建议:
Sterile Filtered colorless solution. The FTH1 protein solution contains 20mM Tris-HCl pH-7.5， 1mM DTT and 10% glycerol.

保存建议：
Ferritin Heavy Chain although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。