重组土拨鼠细胞毒性T淋巴细胞蛋白4(CTLA-4)

特别提示：包括重组土拨鼠细胞毒性T淋巴细胞蛋白4(CTLA-4)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组土拨鼠细胞毒性T淋巴细胞蛋白4(CTLA-4)
英文名称：Recombinant Cavia porcellus Cytotoxic T-lymphocyte protein 4
产品货号：JN1345
产品规格：10μg|50μg|500μg|1mg

本品由我们的酵母表达系统制备而成，目的基因编码的Ala37-Asp161在C端含有His标签。

CTLA-4质量控制：＞95%(还原性SDS-PAGE)

CTLA-4制剂：液体

CTLA-4保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于CTLA-4：
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.

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