EIF4EBP2

产品英文名称：
Recombinant Human SOX9

英文简称:
SOX9

中文名称:
重组人SOX9蛋白

背景资料:
s. SOX9 takes part in chondrocyte di大肠杆菌中重组表达erentiation and， together with steroidogenic factor 1； SOX9 regulates transcription of the anti-Muellerian hormone gene. Deficiencies of SOX9 result in skeletal malformation syndrome campomelic dysplasia， often with sex reversal. SOX9 is a transcription factor having vast mobility group DNA-binding domain that is expressed in all prechondrocytic and chondrocytic cells throughout embryonic growth. SOX9 Phosphorylation by PKA raises its DNA binding and transcriptional activity. SOX9 controls expression of chondrocyte phenotype related genes. IL-1 and TNF-a decrease SOX9 levels of mRNA and/or protein in chondrocytes， therefore strongly inhibit the expression of genes for cartilage extracellular matrix proteins. SOX9 down-regulation takes part in inhibiting expression of the cartilage phenotype in inflammatory joint diseases.

产品描述:
SOX9 Human Recombinant produced in E.Coli is single， a non-glycosylated， Polypeptide chain containing 195 amino acids （316-510 a.a.） fused to a GST tag and having a total molecular mass of 48kDa. The SOX9 is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

序列:


溶解建议:
Sterile Filtered clear solution. SOX9 is supplied in 50mM Tris-Acetate， pH-7.5， 1mM EDTA and 20% Glycerol.

保存建议：
Store at 4℃ if entire vial will be used within 2-4 weeks. Store， frozen at -20℃ for longer periods of time. Please avoid freeze thaw cycles.
其他简介：

  ProSpec是一家全球著名细胞因子蛋白及相关抗体生产和研发品牌。ProSpec的生产和研发工厂位于以色列，专注于蛋白（重组及合成）生产研发，其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子，生长因子，激素，信号蛋白，病毒抗原等近800种重组蛋白和100多种抗体，是世界上提供蛋白品种最多的公司之一，领先的生产工艺和规模使其可以提供毫克到克级蛋白，价格优于同类公司。绝大部分产品是天然成熟型蛋白，而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液，ProSpec-Tany绝大部分产品没有添加保护剂或盐，这就对工艺提出了更高的要求。同时，ProSpec-Tany绝大部分产品为冻干粉，因此易于运输和保存。