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- 规格:
100 µg/1 mg
| 规格: | 100 µg | 产品价格: | ¥3870 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥25190 |
蛋白名称:HER3/ERBB3蛋白, HER3/ERBB3 protein
蛋白构建:A DNA sequence encoding the Rhesus (Macaca mulatta) ErbB3 (XP_001113953.2) extracellular domain (Met 1-Thr 643) was fused with a polyhistidine tag at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 92 % as determined by SDS-PAGE
蛋白活性:1. Measured by its binding ability in a functional ELISA. 2. Immobilized Rhesus ErbB3 at 2 μg/mL (100 μl/well) can bind human NRG1 (isoform Beta1), The EC50 of human NRG1 (isoform Beta1) is 0.58 μg/mL.
蛋白内毒素:< 1.0 EU per μg of the protein as determined by the LAL method
预测N端:Ser 20
蛋白分子量:The recombinant Rhesus ErbB3 consists of 635 amino acids and predicts a molecular mass of 70.1 kDa. As a result of glycosylation, rhesus ErbB3 migrates as an approximately 100 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号:XP_001113953.2
蛋白氨基酸序列:Met1-Thr643
蛋白标签:C-His
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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文献和实验receptor) signaling pathway. The pathway consists of at least four Cell ular receptors: EGFR/HER1, HER2, HER3, and HER4. Approximately 11 different factors are known to bind and activate these receptors in certain patterns. The HER signaling pathway plays
Immunohistochemical Determination of EGFR-Tyrosine Kinase Inhibition in Clinical Samples
The epidermal growth factor receptor (EGFR) family consists of four closely related transmembrane receptors including the EGFR (erbB1), erbB2 (HER2), erbB3 (HER3), and erbB4 (HER4). EGFR (erbB1) was the first member to be described
的苄基部份被替换,与 SNAP-tag 形成共价键。 使用该系统时应包括两个步骤:亚克隆目标蛋白质,使其与 SNAP-tag 形成融合表达蛋白 (fusion protein);选择理想底物标记 SNAP-tag。CLIP-tag 是由 SNAP-tag 衍生而来,经过基因改造,使其不与苄基鸟嘌呤衍生物结合,而与苄基胞嘧啶衍生物(Benzylcytosine)结合。与SNAP-tag 联合使用时,CLIP-tag 能够同时标记同一个细胞中两个不同蛋白质。[/u] 图 1:SNAP-tag
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