Anti-CAPN9 antibody

Anti-CAPN9 antibody

Cat. No.     JC263371   
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CAPN9 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human CAPN9
Reactivity                 Human, Mouse, Rat
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CAPN9
Full name                 calpain 9
Synonyms    GC36; nCL-4
Swissprot    O14815

Target Background
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-CAPN9 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 30-150    Predicted cell location: Cytoplasm
Positive control: Human esophagus cancer
Recommended dilution: 30-150