Anti-DEFA5 antibody

Anti-DEFA5 antibody

Cat. No.     JC261435
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-DEFA5 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human DEFA5
Reactivity                 Human
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 DEFA5
Full name                 defensin, alpha 5, Paneth cell-specific
Synonyms    DEF5; HD-5
Swissprot    Q01523

Target Background
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum.

Anti-DEFA5 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human gasrtic cancer
Recommended dilution: 15-50    Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 15-50