Product overview
Description Anti-ATF2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human ATF2
Reactivity Human, Mouse, Rat
Content 0.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-ATF2 antibody Target information
Symbol ATF2
Full name activating transcription factor 2
Synonyms HB16; CREB2; TREB7; CRE-BP1
Swissprot P15336
Target Background
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene.
Anti-ATF2 antibody Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human lung cancer
Recommended dilution: 15-50