Anti-SNX8 antibody

Anti-SNX8 antibody

Cat. No.     JC223204
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SNX8 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human SNX8
Reactivity                 Human, Mouse
Content                     1 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 SNX8
Full name                 sorting nexin 8
Synonyms    Mvp1
Swissprot    Q9Y5X2

Target Background
Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNXs partially associate with cellular membranes, despite their hydrophilic nature. SNX8 is an ortholog of a yeast protein.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm and Nucleus
Positive control: Human breast cancer
Recommended dilution: 25-100