Anti-CBY1 antibody

Anti-CBY1 antibody

Cat. No.     JC221867
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CBY1 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human CBY1
Reactivity                 Human, Mouse, Rat
Content                     0.6 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 CBY1
Full name                 chibby homolog 1 (Drosophila)
Synonyms    CBY; arb1; PGEA1; C22orf2; PIGEA14; PIGEA-14; HS508I15A
Swissprot    Q9Y3M2

Target Background
Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 50-200