- ￥480 - 860
- TargetMol
- 美国
- T6S1315
- 2026年05月21日
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- 详细信息
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Oroxylin A
- 库存：
10
- 供应商：
TargetMol
- CAS号：
480-11-5
- 规格：
20 mg/1 mL
| 规格： | 20 mg | 产品价格： | ￥860.0 |
|---|---|---|---|
| 规格： | 1 mL | 产品价格： | ￥480.0 |
Product Introduction
Bioactivity
英文名:Oroxylin A
描述:1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production via modulation of LAP/LIP/CHOP in leukemia cell lines, which could providing a therapeutic strategy for RAS. 3. Oroxylin A inhibits UCP2s triggers the MPTP opening, and promotes the apoptosis in CaCo-2 cells; uncoupling protein 2 plays a key role in mitochondrial apoptotic pathway. 4. Oroxylin A inhibits N1ICD translocating to the nucleus and binding to epithelial-mesenchymal transition-related transcription factor Snail, thus suppressing the invasion and migration of MCF-7 cells. 5. Oroxylin A improves the sensitivity of K562/ADM cells by increasing apoptosis in leukemic cells and decreasing the expression of CXCR4 and PI3K/Akt/NF-κB pathway, and probably served as a most promising agent for CML treatment.
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