Product overview
Description Anti-CFL2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CFL2
Reactivity Human, Mouse
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CFL2
Full name cofilin 2
Synonyms NEM7
Swissprot Q9Y281
Target Background
This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Anti-CFL2 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 10-50 Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 10-50