Product overview
Description Anti-CYP2C9 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human CYP2C9
Reactivity Human
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-CYP2C9 antibody Target information
Symbol CYP2C9
Full name cytochrome P450, family 2, subfamily C, polypeptide 9
Synonyms CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9
Swissprot P11712
Target Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
Anti-CYP2C9 antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200