Anti-CENPF antibody

Anti-CENPF antibody

Cat. No.   JC163116
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CENPF rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human CENPF
Reactivity                 Human
Content                     1.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-CENPF antibody
Target information
Symbol                 CENPF
Full name                 centromere protein F
Synonyms    CENF; hcp-1; CILD31; PRO1779
Swissprot    P49454

Target Background
This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.

Anti-CENPF antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 30-150    Predicted cell location: Cytoplasm
Positive control: Human lung cancer
Recommended dilution: 30-150