Product overview
Description Anti-SPN rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human SPN
Reactivity Human
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-SPN antibody Target information
Symbol SPN
Full name sialophorin
Synonyms LSN; CD43; GALGP; GPL115
Swissprot P16150
Target Background
The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response.
Anti-SPN antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 100-300 Predicted cell location: Cytoplasm
Positive control: Human gastric cancer
Recommended dilution: 100-300