Anti-UBTD2 antibody

Anti-UBTD2 antibody

Cat. No.   JC162444      
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-UBTD2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human UBTD2
Reactivity                 Human, Mouse
Content                     0.8 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-UBTD2 antibody
Target information
Symbol                 UBTD2
Full name                 ubiquitin domain containing 2
Synonyms    DCUBP
Swissprot    Q8WUN7

Target Background
UBTD2 (ubiquitin domain containing 2), also known as DCUBP (dendritic cell-derived ubiquitin-like protein), DC-UbP or SB72, is a 234 amino acid cytoplasmic and mitochondrial ubiquitin-like (UbL) protein that contains one C-terminal UbL domain. UbL proteins are involved in a variety of cellular processes, including DNA repair, protein sorting, apoptosis, protein degradation, cell division and autophagy. Predominantly expressed in dendritic cells and detected at high levels in tumor cell lines, UBTD2 has been implicated in apoptosis, cellular differentiation and tumorigenesis. The UbL domain of UBTD2 is 55% similar and 28.6% identical to the amino acid sequence of ubiquitin, but it lacks the Gly-Gly motif that is essential for ubiquitination. As its UbL domain does not actively ubiquitinate proteins, UBTD2 is believed to function as a shuttle factor involved in the ubiquitin system.

Anti-UBTD2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 30-150    Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 30-150