Product overview Description Anti-INTS10 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human INTS10
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol INTS10
Full name integrator complex subunit 10
Synonyms INT10; C8orf35
Swissprot Q9NVR2
Target Background INTS10 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1. INTS10 (integrator complex subunit 10) is also known as INT10 and is a 710 amino acid protein that is localized to the nucleus. INTS10 is a component of the integrator complex and, as such, is thought to aid in the regulation of 3’-end processing of spliceosomal U1 and U2 snRNAs.
Applications Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200 Predicted cell location: Cytoplasm
Positive control: Human lung cancer
Recommended dilution: 50-200