Anti-PPARGC1B antibody

Anti-PPARGC1B antibody

Cat. No.     JC162042        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-PPARGC1B rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human PPARGC1B
Reactivity                 Human
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-PPARGC1B antibody
Target information
Symbol                 PPARGC1B
Full name                 peroxisome proliferator-activated receptor gamma, coactivator 1 beta
Synonyms    PERC; ERRL1; PGC1B; PGC-1(beta)
Swissprot    Q86YN6

Target Background
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Anti-PPARGC1B antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human prostate cancer
Recommended dilution: 25-100