Anti-IPO8 antibody

Anti-IPO8 antibody

Cat. No.     JC161795      
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-IPO8 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human IPO8
Reactivity                 Human, Mouse
Content                     0.9 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-IPO8 antibody
Target information
Symbol                 IPO8
Full name                 importin 8
Synonyms    RANBP8
Swissprot    O15397

Target Background
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. This protein binds to the nuclear pore complex and, along with RanGTP and RANBP1, inhibits the GAP stimulation of the Ran GTPase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Anti-IPO8 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm or Nucleus
Positive control: Human breast cancer
Recommended dilution: 100-300    Predicted cell location: Cytoplasm or Nucleus
Positive control: Human gastric cancer
Recommended dilution: 100-300