Product overview
Description Anti-CIR1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CIR1
Reactivity Human
Content 1 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CIR1
Full name corepressor interacting with RBPJ, 1
Synonyms CIR
Swissprot Q86X95
Target Background
May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.