Anti-NOD2 antibody

Anti-NOD2 antibody

Cat. No.     JC161510    
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-NOD2 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human NOD2
Reactivity                 Human
Content                     0.8 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-NOD2 antibody
Target information
Symbol                 NOD2
Full name                 nucleotide-binding oligomerization domain containing 2
Synonyms    CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1
Swissprot    Q9HC29

Target Background
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome.

Anti-NOD2 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200