Anti-ABCA4 antibody

Anti-ABCA4 antibody

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  • 询价
  • gelatins
  • JC161218
  • 进口/国产
  • 2025年07月06日
  • ELISA, WB
  • Rabbit
  • 人/动物/植物
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    • 详细信息
    • 技术资料
    • 供应商

      上海机纯实业有限公司

    • 库存

      大量

    • 克隆性

      多克隆

    • 保质期

      12个月

    • 抗体英文名

      Anti-ABCA4 antibody

    • 宿主

      Rabbit

    • 适应物种

      人/动物/植物

    • 应用范围

      ELISA, WB

    • 浓度

      0.2 mg/ml

    • 保存条件

      -20°C

    • 规格

      25 μl/100 μl/200 μl

    Anti-ABCA4 antibody

    Cat. No.   JC161218     
    Package    25 μl/100 μl/200 μl
    Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

    Product overview
    Description                   Anti-ABCA4 rabbit polyclonal antibody
    Applications        ELISA, IHC 
    Immunogen               Synthetic peptide of human ABCA4
    Reactivity                 Human
    Content                     0.2 mg/ml
    Host species               Rabbit
    Ig class                  Immunogen-specific rabbit IgG
    Purification                 Antigen affinity purification

    Anti-ABCA4 antibody
    Target information
    Symbol                 ABCA4
    Full name                 ATP-binding cassette, sub-family A (ABC1), member 4
    Synonyms    FFM; RMP; ABCR; RP19; STGD; ABC10; ARMD2; CORD3; STGD1
    Swissprot    P78363

    Target Background
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.

    Anti-ABCA4 antibody
    Applications
    Immunohistochemistry
    Predicted cell location: Membrane, Cytoplasm
    Positive control: Human colon cancer
    Recommended dilution: 25-100    Predicted cell location: Membrane, Cytoplasm
    Positive control: Human thyroid cancer
    Recommended dilution: 25-100

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    资料下载:

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