Anti-SCN1A antibody

Anti-SCN1A antibody

Cat. No.     JC161106        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SCN1A rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human SCN1A
Reactivity                 Human, Rat
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-SCN1A antibody
Target information
Symbol                 SCN1A
Full name                 sodium channel, voltage gated, type I alpha subunit
Synonyms    FEB3; FHM3; NAC1; SCN1; SMEI; EIEE6; FEB3A; HBSCI; GEFSP2; Nav1.1
Swissprot    P35498

Target Background
The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.

Anti-SCN1A antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Nucleus
Positive control: Human cervical cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm, Nucleus
Positive control: Human lung cancer
Recommended dilution: 50-200