Anti-KAT7 antibody

Anti-KAT7 antibody

Cat. No.     JC264317
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-KAT7 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human KAT7
Reactivity                 Human, Mouse, Rat
Content                     1.26 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 KAT7
Full name                 lysine acetyltransferase 7
Synonyms    HBO1; HBOA; MYST2; ZC2HC7
Swissprot    O95251

Target Background
The protein encoded by this gene is part of the multimeric HBO1 complex, which possesses histone H4-specific acetyltransferase activity. This activity is required for functional replication origins and is involved in transcriptional activation of some genes. In both cases, the acetylation of histone H4 helps unfold chromatin so that the DNA can be accessed and replicated or transcribed.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Nucleus
Positive control: Human ovarian cancer
Recommended dilution: 30-150    
            
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ml264317(KAT7 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)    

ELISA
Recommended dilution: 5000-10000