Anti-SUN5 antibody

Anti-SUN5 antibody

Cat. No.     JC263197
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SUN5 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human SUN5
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 SUN5
Full name                 Sad1 and UNC84 domain containing 5
Synonyms    SPAG4L; TSARG4; dJ726C3.1
Swissprot    Q8TC36

Target Background
TSARG4 (testis and spermatogenesis-related gene 4 protein), also known as SPAG4L (sperm-associated antigen 4-like protein) or SRG4 (spermatogenesis-related gene 4) in mice, is a ubiquitously expressed protein in humans but, in mice, it is specifically expressed in the testis. TSARG4 belongs to the spindle pole body family of proteins and contains one Unc84/SUN domain and a potential transmembrane region. The human TSARG4 protein shares 74% amino acid identity with its mouse counterpart. In mice, TSARG4 is found in round spermatids and spermatocytes and may participate in mitosis. It has been hypothesized that TSARG4 localizes to the nuclear envelope.

Applications
Immunohistochemistry
Predicted cell location: Nucleus or Cell membrane
Positive control: Human lung cancer
Recommended dilution: 20-100    Predicted cell location: Nucleus or Cell membrane
Positive control: Human brain
Recommended dilution: 20-100
            
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using ml263197(SUN5 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml263197(SUN5 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)

ELISA
Recommended dilution: 5000-10000