Anti-SETD1A antibody

Anti-SETD1A antibody

Cat. No.     JC264218
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SETD1A rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human SETD1A
Reactivity                 Human
Content                     1.08 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 SETD1A
Full name                 SET domain containing 1A
Synonyms    Set1; KMT2F; Set1A
Swissprot    O15047

Target Background
The protein encoded by this gene is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. Trimethylation of histone H3 at lysine 4 (H3K4me3) is a chromatin modification known to generally mark the transcription start sites of active genes. The protein contains SET domains, a RNA recognition motif domain and is a member of the class V-like SAM-binding methyltransferase superfamily.

Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 40-200    
            
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml264218(SETD1A Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)    

ELISA
Recommended dilution: 5000-10000