Anti-HNRNPAB antibody

Anti-HNRNPAB antibody

Cat. No.     JC264202
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-HNRNPAB rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human HNRNPAB
Reactivity                 Human, Mouse
Content                     0.24 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 HNRNPAB
Full name                 heterogeneous nuclear ribonucleoprotein A/B
Synonyms    ABBP1; HNRPAB
Swissprot    Q99729

Target Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 20-100    Predicted cell location: Nucleus
Positive control: Human tonsil
Recommended dilution: 20-100
            
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml264202(HNRNPAB Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml264202(HNRNPAB Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:36 kDa
Positive control:Jurkat cell, Human fetal brain tissue lysates 
Recommended dilution: 200-1000