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- 详细信息
- 文献和实验
- 技术资料
- 库存:
100
- 供应商:
上海羽朵生物科技有限公司
- 检测方法:
ELISA
- 应用:
ELISA
- 规格:
48T
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文献和实验18 Direct Sequencing for Cowden Syndrome Gene PTEN (MMAC1) Mutations
Cowden syndrome is a rare dominantly inherited condition with predisposition to benign hamartomatous polyposis of the intestine, as well as malignant tumors of the breast and thyroid, and possibly some other cancer types. Other features include
Genetic evidence strongly suggested that a tumor suppressor was located on chromosome 10. During the development of glioblastoma, one copy of chromosome 10 was typically lost (1 ). Cytogenetic and molecular analysis revealed partial
Measurement of PTEN Activity in vivo by Imaging Phosphorylated Akt
This chapter describes an indirect approach to measure PTEN’s lipid phosphatase activity in vivo . PTEN counteracts phosphatidylinositol 3-kinase action in dephosphorylating 3-phosphorylated phosphoinositides. Therefore, PtdIns(3,4,5)P3
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